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MARIE CURIE Postdoc fellows opportunity!

We have been highly successful in securing Marie Curie fellowships in the past (4 fellows) and we are looking to expand our current team (including 2 MSCA postdoctoral fellows, 2 MSCA PhD fellows). Our laboratory is particularly interested in what drives pathological processes during the development of epilepsy and how interfering with the purinergic system impacts on the disease. For our research we use a range of newly developed transgenic animal models, patient tissue and a variety of in vitro approaches including human-induced pluripotent stem cells.

We are interested in speaking with postdoctoral researchers with ideally a strong background in neuroscience, who would work on an exciting new project based around purinergic signalling in epilepsy taking advantage of novel technologies (e.g., single cell sequencing, iPSCs). Our group has strong collaborations with industry (e.g., Janssen and Affectis) and is based at the Royal College of Surgeons in Ireland (RCSI).

RCSI has been at the forefront of educating healthcare professionals since 1784 when we were founded as the national training and professional body for surgery. Today we are Ireland’s only focused health sciences institution, Ireland’s largest medical school and one of the leading health sciences institutions in the world. RCSI hosts a multi-cultural environment with state-of-the-art facilities in the heart of Dublin, Ireland.

For more information contact Dr Tobias Engel (

December 2018

Profiling of Argonaute-2-loaded microRNAs in a mouse model of frontotemporal dementia with parkinsonism-17

Tauopathies are a group of neurodegenerative diseases characterized by the pathological aggregation of the microtubule-associated protein tau. These include more than 20 diseases, with Alzheimer’s disease being the most frequent. While pathological and neurotoxic effects of tau are well documented, the mechanisms by which tau can promote neurodegeneration are less clear.