The Purines Epilepsy lab Principal Investigator Tobias Engel will be a guest lecture on the Biomedical Biosensor SMARTChip and Probe Workshop hosted by Sarissa on March 22nd.
More information can be found here.
Profiling of Argonaute-2-loaded microRNAs in a mouse model of frontotemporal dementia with parkinsonism-17
Tauopathies are a group of neurodegenerative diseases characterized by the pathological aggregation of the microtubule-associated protein tau. These include more than 20 diseases, with Alzheimer’s disease being the most frequent. While pathological and neurotoxic effects of tau are well documented, the mechanisms by which tau can promote neurodegeneration are less clear.
* Seizure-induced ATP release widely considered to contribute to epileptogenesis. * Evidence for P2 receptor role in epileptogenesis well established. * Evidence for seizure-induced ATP release mixed and dependent on model and method of detection.
James Morgan, PhD candidate in the PurinesDX programme coordinated by our group won the best poster prize in the the Postgraduate Scholars first year only category during RCSI Research Day on March 7th, with poster entitled: “Identification of the cell-specific contribution of the P2X7 receptor to seizure-induced pathology and epilepsy development”
We are based at the Royal College of Surgeons in Ireland.
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